剧情主线围绕两名底层列车乘务闺蜜展开，二人从破旧老旧铁路调职到奢华顶级高速列车，本以为迎来轻松光鲜的工作，途中突发超强极端风暴,列车控制系统彻底失控、轨道损毁，整趟列车全速朝着洛杉矶城区直冲，一旦撞击将造成毁灭性伤亡。两名主角被迫放下阶层隔阂，与高傲挑剔的一等舱精英乘务组、由鲁保罗饰演的总统紧急联手，在高速失控的列车上一路闯关抢修设备、化解车厢内乱、应对极端天气险情，在夸张闹剧、变装秀、歌舞桥段与紧张逃生动作场面并行之下，拼尽全力逼停列车!
演員: RuPaul
/ Jujubee
/ Ginger Minj
/ Brooke Lynn Hytes
/ Marcia Marcia Marcia
/ Symone
/ Latrice Royale
/ Rachel Bloom
/ Angeria Paris VanMicheals
/ Brian Jordan Alvarez
/ Chris Parnell
/ Guy Branum
/ Charo
/ Monét X Change
/ Drew Droege
/ 傑西·泰勒·弗格森
/ Daniel Franzese
/ Natasha Leggero
/ Michelle Visage
/ Riki Lindhome
/ Jai Rodriguez
/ Mayan López
/ Paul Scheer
/ Joel McHale
/ Evan Mulrooney
/ 傑瑞·歐康諾
/ Nicole Sullivan
/ Missi Pyle
/ June Diane Raphael
/ Raven-Symoné
/ Nicole Richie
/ Lisa Rinna
/ Matt Rogers
/ Sarah Michelle Gellar
/ Brock Yurich
/ Asher Alexander
/ J.P. Manoux
/ Bryce Eilenberg
/ Bruno Carvalho Alcantara
/ Cliff Jensen
